Science Dudes: Biology

Mitotic Cell Division Stages, Diagrams, & Summary (Explained!)

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This article is about Mitosis Cell division and different stages of mitotic cell division.<br />
<br />
Mitosis is an equatorial division in which a mother cell divides to form 2 daughter cells. This was first observed by a German biologist, <i>Walter Flemming</i>, in 1877 AD.<br />
<br />
Mitosis takes place in vegetative or somatic cell. So, it is also called <b>Somatic Cell Division</b>.<br />
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In general, mitosis is preceded by the 5 stages of Interphase ( During which the DNA is replicated). Then, it is often followed by cytokinesis, which divides the cytoplasm, organelles, and cell membrane into 2 new cell containing roughly equal shares of these cellular components. We will discuss each of these stages in details below.<br />
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In mitotic cell division, the same number (diploid number) of chromosomes of the parent cell is maintained in each division of the cell. <i><u>The cell division in which a diploid parent cell divides biologically into 2 diploid daughter cells is called mitotic cell division.</u></i><br />
<i><u><br /></u></i>
Let's get into mitosis cell division stages.<br />
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<h2 style="text-align: left;">
Interphase</h2>
Interphase is the non-dividing phase of Mitosis. In this phase, the actual cell division doesn’t occur. It is a phase of high metabolic activity, in which a cell makes all necessary preparations required for cell division. Interphase itself has is divided into 3 phases, namely G1 (first gap), S (synthesis), and G2(second gap).<br />
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During these 3 stages, the following activities take place:<br />
<br />
<ul style="text-align: left;">
<li>the cell grows by producing protein, and cytoplasmic organelles </li>
<li>Replication of DNA, and synthesis of histone protein take place which results in duplication of chromosomes</li>
<li>Chromosomes are replicated only during the "S" phase</li>
</ul>
In animal cells, the centrosome begins to divide. Chromosomes appear in the form of diffused, long & coiled network called chromatin fibers.<br />
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<div>
<h2 style="text-align: left;">
Phases of Mitotic Cell Division</h2>
Mitosis is a continuous process. M<span style="background-color: white; font-family: "arial"; font-size: 13px; white-space: pre-wrap;">itosis cell division occurs in following 4 stages:</span><br />
1) Prophase<br />
2) Metaphase<br />
3) Anaphase<br />
4) Telophase<br />
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<h3 style="text-align: left;">
Prophase (pro = before, phasis = stage)</h3>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjtSyUILXEOrLyXZUL_bI_QIefQOTwcvCSAPk8WSu8Pcge8Cdf8Wlyz3te_a0fcCj8aaQk6ACT3ThbXEA3OfSaN97eMsFFdcOMVjh1ORZVOg_dZAk-i9iuC_GcTWhQ_zunB9nKS9RIGIds/s1600/earlyprophase.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="stages of mitotic cell cycle" border="0" data-original-height="229" data-original-width="217" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjtSyUILXEOrLyXZUL_bI_QIefQOTwcvCSAPk8WSu8Pcge8Cdf8Wlyz3te_a0fcCj8aaQk6ACT3ThbXEA3OfSaN97eMsFFdcOMVjh1ORZVOg_dZAk-i9iuC_GcTWhQ_zunB9nKS9RIGIds/s1600/earlyprophase.png" title="" /></a></div>
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It is the first and longest stage of mitosis cell division. It lasts for 100 minutes. This stage involves a number of changes in the cell which take place simultaneously. In this stage, chromosomes are long, thin, and are like a thread. Each chromosomes has two chromatids. The two chromatids are joined at the centromere. The chromatin material condense into distinct thread like structure called a centromere and 2 sister chromatids which becomes shorter and thicker as the prophase proceeds. Nucleolus and nuclear membrane start disappearing towards the end of prophase. The two centrioles of the centrosome migrate towards opposite poles by forming spindle fibers.<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiCLaYJLNWm-DmHvl4xXE9l8GjL0yKA2XvlIDuCIuiIAQMBNycxu_kmmKj06-no7eM7Oxpt0iFlZ2FJqAPyGnI2-bDd2Z_B2nxsukmxLALkOadmD0j-atnt-EDWaMzRBdd6mx5AKFQkrDE/s1600/lateprophase.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="mitotic cell division in animal cell" border="0" data-original-height="221" data-original-width="175" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiCLaYJLNWm-DmHvl4xXE9l8GjL0yKA2XvlIDuCIuiIAQMBNycxu_kmmKj06-no7eM7Oxpt0iFlZ2FJqAPyGnI2-bDd2Z_B2nxsukmxLALkOadmD0j-atnt-EDWaMzRBdd6mx5AKFQkrDE/s1600/lateprophase.png" title="" /></a></div>
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<h3 style="text-align: left;">
Metaphase (meta = between, phasis = stage)</h3>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhfhrIeQMmAJRFnRG2NlL-UTR7zdf_YSsAotR3SUHDvKENqTbhSbvYRS7Sl952ZECHsGSIIqAwOt8KlaDeY7pRfW_8x6T7QDfSOubmQVM-zsFM1C-a3apQeg_hGm-iL2aDKxLLG8tOZvXg/s1600/metaphase.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="describe the process of mitotic cell division" border="0" data-original-height="274" data-original-width="148" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhfhrIeQMmAJRFnRG2NlL-UTR7zdf_YSsAotR3SUHDvKENqTbhSbvYRS7Sl952ZECHsGSIIqAwOt8KlaDeY7pRfW_8x6T7QDfSOubmQVM-zsFM1C-a3apQeg_hGm-iL2aDKxLLG8tOZvXg/s1600/metaphase.png" title="" /></a></div>
It is the second stage or middle stage of mitosis which lasts for 15 minutes. In this stage, nucleolus and nuclear membrane disappear completely and nuclear spindle appears. Chromosomes come to lie on equator and arms face towards poles. Spindle fibers attach themselves to centromere of chromosome whereas chromosomes becomes shorter and thicker due to condensation.<br />
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<h3 style="text-align: left;">
Anaphase (ana = back, phasis = stage)</h3>
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It is the third and shorter stage of mitotic cell division. This stage last for 10 minutes. In this stage, centromeres of each pair of chromatids appear to repel each other and are separated forming two daughters chromosomes. Whereas, chromosomes migrate towards opposite poles due to the contraction of spindle fibers and repelling force of sister chromatids and becomes shorter and thicker, and take the shape of "U" ,"V" or "J" depending on the position of centromere.<br />
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<h3 style="text-align: left;">
Telophase (telo = end, phasis = stage)</h3>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjUlmqNsKD-ybdiniX4ptc4BpWlhthHcH_7J4zMCdAZFN7D0bLt_95V9lvNb1BghflmGaB-jAVs8-xkmTcWrm1pd9XFe2dRB9ckP6u7FA9JDD25COnAZkRJcqQJ9eQtDYnihWHCqZvDOIE/s1600/telophase.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="about mitosis cell division" border="0" data-original-height="275" data-original-width="190" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjUlmqNsKD-ybdiniX4ptc4BpWlhthHcH_7J4zMCdAZFN7D0bLt_95V9lvNb1BghflmGaB-jAVs8-xkmTcWrm1pd9XFe2dRB9ckP6u7FA9JDD25COnAZkRJcqQJ9eQtDYnihWHCqZvDOIE/s1600/telophase.png" title="" /></a></div>
It is the fourth and last stage of karyokinesis. During this stage, the events of prophase occurs in reverse sequence. It last for 60 minutes. The daughter chromosomes reach their respective poles, uncoil, and change into chromatin network. Nuclear membrane reappears around the chromatin network of each pole.<br />
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Therefore, two daughter nuclei with same number of chromosomes are formed.<br />
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Nucleolus appears in each daughter nucleus and spindle fibers disappear.<br />
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In animal cell, the centromere organizes itself above the nucleus at the end of karyokinesis.<br />
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At the end of telophase, karyokinesis is followed by cytokinesis. i.e - division of cytoplasm.<br />
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<h3 style="text-align: left;">
Cytokinesis (cyto = cell, kinesis= movement)</h3>
In this stage, the cytoplasm actually divides. In this stage, nuclear division occurs.<br />
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The process is slightly different between animals and plants cell.<br />
In animal cells, there are actin filaments. These filaments interacts with each other causing the cell membrane to create cleavage furrow in them. The furrow then deepens, and eventually results in division of cell membrane to form two individual cells.<br />
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In plant cell, it has a rigid cell wall. Cytokinesis is accompanied by cell plate formation. In this process, a new cell plate is formed in the middle of the cell. This cell plate continues to grow so that it reaches the cell membrane and finally combines with the cell’s original plate. Now the newly formed plate breaks forming two individual cells.<br />
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<h2 style="text-align: left;">
Summary</h2>
<div>
<br /></div>
<h3 style="text-align: left;">
Prophase</h3>
In brief the following things occur during prophase:<br />
<ul style="text-align: left;">
<li>DNA condenses to form chromosomes</li>
<li>Nuclear membrane starts to fade
Nucleolus disappears</li>
<li>Centrioles start making spindle fires</li>
</ul>
<div>
<br /></div>
<h3 style="text-align: left;">
Metaphase</h3>
<br />
<ul style="text-align: left;">
<li>Chromosomes are joined by two spindle fibers</li>
<li>Chromosomes arrange themselves at the equatorial plane</li>
<li>Formation of equatorial phase occurs</li>
</ul>
<div>
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<h3 style="text-align: left;">
Anaphase</h3>
<br />
<ul style="text-align: left;">
<li>Spindle fibers shorten so that chromosomes pair separate and are taken towards each pole.</li>
</ul>
<div>
<br /></div>
<h3 style="text-align: left;">
Telophase</h3>
<br />
<ul style="text-align: left;">
<li>Separation of chromosomes complete in this phase</li>
<li>In animals cell, cleavage furrowing occurs</li>
<li>In plants cell, cell plate forms</li>
<li>Reformation of nucleus and nucleolus
Chromosomes uncoil</li>
</ul>
</div>
</div>
</div>

Mitotic Cell Division Stages, Diagrams, & Summary (Explained!)

This article is about Mitosis Cell division and different stages of mitotic cell division. Mitosis is an equatorial division in which ...

Cell Division Meaning, Definition, and Types For Dummies (Explained!)

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<h3 style="text-align: left;">
What is a Cell?</h3>
A biological cell is defined as the fundamental, structural, and functional unit of life. The bodies of living organisms are made up of microscopic units known as cells. Cells, themselves, are made up of a life giving substances called protoplasm, cell organelles, and inclusions.<br />
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<h3 style="text-align: left;">
Define Cell Division</h3>
<div>
The biological process in which an existing cell divides into two or four daughter cells is called cell division.<br />
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<h3 style="text-align: left;">
Why Does Cell Division Occur?</h3>
<div>
Cell division is a vital part of life. Our bodies grow because of cell division. When older cells die, new cells must replace their position. Similarly, <b>cell division helps in reproduction.</b> Cell division is essential for continuity of a species. All of the structure of a parent cell are duplicated in cell division and divides into two or more daughter cells. In unicellular organisms, cell division is a means of reproduction because it directly produces two daughter organisms.<br />
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<div>
Cell division has 3 important aspects:<br />
<ol style="text-align: left;">
<li>Replication of DNA</li>
<li>Karyokinesis (division of nucleus), </li>
<li>and Cytokinesis (division of cytoplasm). </li>
</ol>
<div>
In cell division, the Karyokinesis is followed by Cytokinesis.<br />
<br /></div>
<h3 style="text-align: left;">
Types of cell division</h3>
On the basis of mode of nuclear division, cells are divided into 3 different ways.<br />
They are:<br />
<ol style="text-align: left;">
<li>Amitosis (also known as Binary fission)</li>
<li>Mitosis</li>
<li>Meiosis

</li>
</ol>
<div>
In the next post, we will explore each of these types in details.</div>
</div>
</div>

Cell Division Meaning, Definition, and Types For Dummies (Explained!)

What is a Cell? A biological cell is defined as the fundamental, structural, and functional unit of life. The bodies of living organi...

Discuss The Role Of Chromosomes in Cell Division and Inheritance/Heredity

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Wondering what does chromosomes do during cell division? This article provides superficial explanation of the main function of chromosomes in cell division and in inherited traits and characteristics.<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiFX29UjNF4ZxuYSxYhRTyvnXPnFa5__oOALebd3azpTHtoG3GnHn8Pc-CFhX8REJkJa7h45U2PXS2Emo_gj-KMNYVMtOpsZuxAxNFnAgVsCAzAwXzidxgLjuP02uxYoiiHnD0QTvpGvrs/s1600/Steel+Blue+People+Men%2527s+Fashion+Facebook+Post-2.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="Role Of Chromosomes in Cell Division and Inheritance" border="0" data-original-height="789" data-original-width="940" height="268" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiFX29UjNF4ZxuYSxYhRTyvnXPnFa5__oOALebd3azpTHtoG3GnHn8Pc-CFhX8REJkJa7h45U2PXS2Emo_gj-KMNYVMtOpsZuxAxNFnAgVsCAzAwXzidxgLjuP02uxYoiiHnD0QTvpGvrs/s320/Steel+Blue+People+Men%2527s+Fashion+Facebook+Post-2.png" title="" width="320" /></a></div>
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Chromosomes are the organized structure of DNA(Deoxyribonucleic Acid) and protein which is found in nucleus of both plant and animal cells. Before a cell divides, the chromosome are replicated within the nucleus. In a human cell, the nucleus of cell division contains 46 pair of chromosomes. Organisms grow by undergoing cell division to produce new cells and replace older one. As the genetic material passes from parents to child, <b>the chromosomes are responsible for containing the instructions that makes the offspring unique while still carrying traits from the parents</b>. It's essential that certain cells, like reproductive cell, have correct number of chromosomes in order to function properly. It also helps to ensure that the DNA should be remain tightly around the proteins otherwise DNA molecules will be larger in the inside of cells.</div>

Discuss The Role Of Chromosomes in Cell Division and Inheritance/Heredity

Wondering what does chromosomes do during cell division? This article provides superficial explanation of the main function of chromosomes ...

Fish Swim in Water With The Help Of? Movement Of Fish in Water

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You might be wondering why can fishes swim in water but many other animals cannot? Well, it's because they have some special parts which enable them to swim inside water.<br />
<br />
How to describe fish swimming?<b> </b>Well, <b>Fish swim in water with the help of Fins</b>. Unlike most animals, fishes do not have limbs. They rely entirely on their fins for their locomotion. The picture below shows the fins of a fish.<br />
<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhaDqOTuMI5HAzIVjueQQM5a9cpghfX7nFrs03akUpDTxj-JkfmyutuCFNWAq4xKUAa_Uq_pVIF5wyS5VfleTgjDGA7BnJXx8tt1p32gXlMRZBgUWx5qLuSpNK-YMNIFO3fA78MS5Gydwo/s1600/fish-1346521_960_720.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img alt="how do fishes swim in water" border="0" data-original-height="526" data-original-width="960" height="175" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhaDqOTuMI5HAzIVjueQQM5a9cpghfX7nFrs03akUpDTxj-JkfmyutuCFNWAq4xKUAa_Uq_pVIF5wyS5VfleTgjDGA7BnJXx8tt1p32gXlMRZBgUWx5qLuSpNK-YMNIFO3fA78MS5Gydwo/s320/fish-1346521_960_720.jpg" title="" width="320" /></a></div>
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The size and number of fins in any fish can differ from another fish. Generally, fishes of same breed have same number of fins but it can differ. Fishes have streamlined body which helps them swim in water. As you see in the above picture, fishes have different kind of fins. Each of them has their own function. Fins can be in pair or unpaired. Unpaired fins help fishes to maintain balance while swimming. The fin near their tail, called "Tail Fin", helps them move forward, acting like a propeller. Fishes also have pectoral fins which help them to change or maintain direction. Check the animated image below. See how these fishes uses their pectoral fin to change their direction?<br />
<br />
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiM8iCzAW8u5cMOpxC_jxr4s7oz8ZeMeqsm0TJDohEOPyTIq0wRZ1SIXq1Psae8rqFxoswXm4PsrzaodSNtwzey-36u9ZihAgK-AR2KweOuTo-PsjeV3N34VUSubkN9tZoTofzI7eKZBbA/s1600/goldfish.gif" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="450" data-original-width="600" height="240" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiM8iCzAW8u5cMOpxC_jxr4s7oz8ZeMeqsm0TJDohEOPyTIq0wRZ1SIXq1Psae8rqFxoswXm4PsrzaodSNtwzey-36u9ZihAgK-AR2KweOuTo-PsjeV3N34VUSubkN9tZoTofzI7eKZBbA/s320/goldfish.gif" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Taken From Genome.gov</td></tr>
</tbody></table>
</div>

Fish Swim in Water With The Help Of? Movement Of Fish in Water

You might be wondering why can fishes swim in water but many other animals cannot? Well, it's because they have some special parts ...